Low Vitamin C Linked to Cataract Formation by Anne Scheck

We found this interesting article in EYENET, February 2012, by Anne Scheck. 

In a recent study, a strong association between vitamin C deficiency and cataract formation has been documented amount adults in India's lower- and middle- income population.

The study involved more than 5,500 men and women 60 years of age or older.  Researchers measured plasma vitamin C in all participants, along with other anti-oxidants such as alphatocopherol and betacarotene.  The investigation controlled for lifestyle influences, such as alcohol consumption and tobacco use, nurtitional status, blood pressure, midday sun exposure and body mass index.  The dramatic inverse relationship between vitamin C depletion and the presence of all types of cataracts was seen in groups from both northern and southern parts of the country.  Gender made no difference.

Low levels of vitamin C didn't seem to impact overall health in observable ways, and the precise mechanism through which depletion might affect cataract etiology remains elusive, said Ravilla Ravindran, MSDO, lead author of the investigation and chairman of Aravind Eye Care System in Madurai, India.  He noted that it is not yet established whether lack of vitamin C is a cause, contributing factor or a trigger for an underlying process that predisposes individuals to developing cataracts. 

It is time to determine whether a vitamin C- enriched diet might protect against cataract in a population similar to his study group, said Dr. Ravindran.  "We are looking at conducting a prevention study; it is under discussion."

1     Ravindran RD et al. Ophthalmology.  2011; 118 (10):  1958-1965.
Dr. Ravindran and his coauthors have no financial interest in the subject of this study.

Comments

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